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To reflect the changing face of undergraduate and postgraduate

medical education, this new edition emphasises the principles of

disease processes and their underlying mechanisms, bringing the

content up to date with the latest developments from the fields of

molecular and cellular biology. The focus is on describing the

fundamental features of pathophysiological processes with examples

to illustrate the similar mechanisms underlying apparently diverse

clinical conditi***. By understanding the cellular in***cti*** in

one disease area, similar principles can be applied to other

disease groups and to the scientific basis of medical management

and treatment strategies. Throughout, the student is encouraged to

evaluate and integrate the evidence critically, developing skills

for self-directed learning and the application of knowledge. To

further encourage the reader to integrate the theory with clinical

practice, each chapter concludes with a series of clinical

scenarios and MCQs, with answers provided.

1. Molecular and cell biology Julian R. E. Davis

2. Hereditary disease Timothy M. Cox

3. Obesity J. Shaker, P. G. McTernan and Sudesh Kumar

4. Autoimmune mechanisms Anthony A. P. Weetman

5. Allergy: anaphylaxis Richard S. H. Pumphrey

6. Infection - Bacteria Stephen D. Lawn and Ge***e E. Griffin

7. Infection - Parasite E. M. Molyneux

8. The acute coronary syndrome Anthony M. Heagerty

9. Heart failure Ludwig Neyses and M. H. Buch

10. Acute neurodegeneration: cerebral ischaemia and stroke Craig J

Smith, Jerard Ross, Nancy J. Rothwell and Pippa J. Tyrell

11. Diabetic neuropathy A. Greenstein, M. Mojaddidi, A. J. M.

Boulton and Rayaz A. Malik

12. Renal cell carcinoma W. Mansoor

13. Toxic mechanisms James Neuberger

14. Diet, health and disease Michael E. J. Lean

15. Trauma Nick Payne and David Yates

16. The in***ction between ***anic and psychiatric disease Elspeth

Guthrie

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书籍介绍

To reflect the changing face of undergraduate and postgraduate medical education, this new edition emphasises the principles of disease processes and their underlying mechanisms, bringing the content up to date with the latest developments from the fields of molecular and cellular biology. The focus is on describing the fundamental features of pathophysiological processes with examples to illustrate the similar mechanisms underlying apparently diverse clinical conditi***. By understanding the cellular in***cti*** in one disease area, similar principles can be applied to other disease groups and to the scientific basis of medical management and treatment strategies. Throughout, the student is encouraged to evaluate and integrate the evidence critically, developing skills for self-directed learning and the application of knowledge. To further encourage the reader to integrate the theory with clinical practice, each chapter concludes with a series of clinical scenarios and MCQs, with answers provided.